Dr. Tan and Partners is one of the few approved Anonymous HIV Testing Centres in Singapore. A detailed write up on our service is available here.

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HIV 4th Generation Test Singapore

The HIV 4th Generation Test is one of the most accurate and fastest way to determine is a person has been infected with HIV or not.

The HIV 4th Generation Test is also called the Combo test or the Duo test.

It tests for both the HIV antibodies as well as the antigens in the blood. It can be done as a rapid test i.e. you can get the results in 20 minutes.

Antibodies are produced by the body when it is infected with the HIV virus. There are many different types of antibodies. The one that is produced the earliest is called the IgM antibody. This can be produced as early as 20 days post exposure. 3rd and 4th Generation HIV tests can detect the IgM antibody.

Antigens are bits of the HIV virus shell that can be found in the blood as early as 14 days post exposure. The 4th Generation test can detect the presence of this antigen.

If the test detects either the presence of HIV antibodies or antigens, it means the patient is most likely infected with HIV. This has to be confirmed with another ELISA test. We always do at least 2 tests before diagnosing a person as HIV +ve.

Officially it is conclusive at 28 days post exposure. However, from current scientific data, we know that when the test is done at 20 days post exposure, it is already as good as 100% accurate. Personally I have tested patients +ve for HIV at only 14 days post exposure with this test.

The US CDC recommends the HIV 4th Generation test for all HIV screening. This is because it is more accurate, has a shorter window period and can pick up rare cases of sero-negative infections (see below).

The HIV 4th Generation test can detect HIV infections in very rare cases of people who are infected with HIV but never produce any anti-bodies. These are called sero-negative infections and happen in about 1 in 1 million people.

At our clinics the HIV 4th Generation test costs $150 (before GST).

You can walk in our clinics at Robertson Walk, Bencoolen Street, Novena Medical Center or Scotts Road anytime during our opening hours for this test. It only requires a finger-prick of blood and 20 minutes to get results.

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If you need a HIV test visit Our Clinics anytime during our opening hours. You do not need an appointment.

 

Find out more about Anonymous HIV testing at our clinics.

Can’t wait for 3 months to find out? Find out more about Anonymous Rapid HIV Combo test at our clinics.

If you had a high risk exposure to HIV within the past 72 hours, you can take medicines to reduce your risk of actually contracting HIV. Find out more on HIV PEP Treatment.

 

Related Topics:

Anonymous HIV testing at our Clinics

HIV – Understanding the Window Period

Cost of HIV/STD tests at our Clinics

Condom Broke

Getting HIV from Oral Sex

More on HIV symptoms

How long can HIV live outside the body?


 

 

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Need more advice?

Come down to Our Clinics for a discussion with Our Doctors, or call our clinics for more information:

1.) Robertson Walk (Anonymous HIV Clinic)  (+65 6238 7810)

2.) Bencoolen Street (+65 6884 4119)

3.) Novena Medical Centre (+65 6397 2095)

4.) Scotts Medical Centre (+65 6694 2348)

5.) Somerset – Orchard Building (+65 6262 0762)

6.) Katong – East Coast Road (+65 6635 2551)

 

Where to find us – here

Selected clinics are open on Saturday and Sunday.

 

Email: [email protected]

 

All Our Doctors are Fully Certified and Trained to conduct specialised HIV Testing.

 

For lady patients who prefer female doctors, we have professional certified female Doctors to attend to your medical needs.

About Dr. Tan
Dr. Tan graduated from the National University of Singapore in 2001. His residency was in the two largest public hospitals in Singapore; Tan Tock Seng Hospital and Singapore General Hospital.

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880 Comments

  1. dear doctor

    why indian doctor is not agree on DUO test negative is not comsider conclusive at at 9 week?? i told them famouse doctor from singapur Dr. Tan is always saying DUO test 100% comclusive at 9 weeks and no need to further testing.. kindly help.me with logic about DUO test behind of this…is it 100 % conclusive at 9 weeks?????

    1. when antibody is started in blood then they attack on p24 antigin????

    its means DUO test at any time if anyibody is not in blood then p24 antigin always available nefore antibody started??

    i want to give answer to my indian doctor becouse i think he dont have enough knowledge ..so please give me answer in detail.. thanks

  2. Hi Doc

    Would a cycle of testosterone enanthate (anabolic steroids)have any effect on an hiv combo test? Ive tested neg at 16 weeks on a duo test!! Is this considered conclusive??

    • No, it would not affect your result. It is considered conclusive.

      • Hi Doctor,

        In your opinion, are below test conclusive for HIV

        HIV AB/AG (CMIA) – 38day – Non reactive
        HIV Rapid Test AHP (Finger prick) – 83day – Negative

        Do you agree test result overrule symtomp?

  3. Is 60 days hiv duo combo is conclusive???

  4. Dr. Murli

    Dear Dr.Tan

    i am HIV specialist from Sri Lanka. i have some questions for you..

    1. how much you sure about 4th generation DUO combo test is comclusive at 28 days and why?

    2. In what Basis you are telling poor people no need to test after 28 days negative??

    3. if any pateint will take time to make antibody after p24 disappear ..then who will resposible.

    4. for example.. if someone test at 9 week and p24 not available and antiboday take time then thier is chances of false negative?? EXPLIN ME THIS POINT……

    5. so what do u think 28 days is very risky to advise people to move on…i am right??

    answer me here only please so people will make sure thier daughts..

    if p24 disappear then tested is worth if someone not make antibody??

    please focus on poimt 4

    thanks in.advance

    • You are clearly not an HIV specialist as you purport to be if you are asking these questions. The p24 antigen levels will only reduce in response to rising antibody titres. There is no period (especially at 9 weeks) where antigen will be negative and antibody has not reached a detectable level.

      • Dr. Murli

        j said i an working with very famouse hiv specialist..i am juniour..

        is someone tested at 9 week wwith 4th generation what you will not suggest him to test if symptomps also thier??

        thans

        • Your story makes no sense. If you work with a “famous HIV specialist” wouldn’t you rather speak to them in person with your questions instead of posting comments on a website for a clinic in Singapore? Stop wasting our time please.

  5. dood morning doctor.

    i had big mistake. unprotected vagina sex for short time..after 62 days i had 4th grneration CMIA blood test from lab and its negative. please doctor tell me if it is conclusive

    1. any chances if falls negative at 62 days

    2. can i repeat test at 12 weeks??

    thanks and apriciate to your good job for helping people

    • The 4th gen test is conclusive at 28 days or more. You can repeat your test if you wish but I do not believe it is necessary.

  6. Anthony

    hello doctor

    after unprotected vagina i did 4th generation test at 7.5 week in your lab. thanks god is negative. how many chances of false negative?? and do i need any testing further. thanks please reply me in detail.

  7. hii doctor

    after unprotected vagina sex for 10 seconds i did 4th generation duo CMIA test at 8 weeks negative. but i have red hand palm from last two months. and many pimples on back..is my result is 100% correct or i need one more test at 12 weeks?? is thier anybchance of false negative ag 8 weeks… pls reply me in detail

    thanks for helping

  8. hii doctor

    i tested 4th generation duo combo at 9 week negative..can i assume this is my final test. vagina unprotecyed sex

  9. i had rapid hiv combo test after 77 days from the exposure it was unprotected viginal sex but i’m still scared can i move on ? anyway and do rapid hiv combos test results come after 2 hours ?cuz the doctor said i go back to her after 2 hours and the blood they took it from my vein

  10. Hi doctor,

    Is there a different for 4th generation rapid test kit and 4th generation lab test? Are the window period the same?

  11. Ravi shankar

    Is there any pcr test for HIV2 early detection. Most of the health clinic i see offer only HIV 1 PCR test.

  12. Would it be conclusive at 33th day after exposure for a elisa 4 th gen test?

  13. Dear Dr an anwer would be highly appreciated.

    Would a negative HIV Duo test (Cobas by Roche) at 35 days and 53 days rule out infection even for HIV type 2?

    Many thanks,

  14. James ong

    How accurate is elisa test ab/ag at 26 days post exposure which is two days short of the recommended 28 days. Is it conclusive as well?

  15. Hi, Would a negative HIV at 35 days and 53 days rule out infection even for HIV type 2?

  16. Hello Dr I have a ? I tested negative with the hiv duo test post 20 days after exposure the exposure was the 10th of November and I tested the 30th should i re test or how conclusive is my result

  17. First thank u for responding and respecting tha questions

    I had 4th generation hiv test after 30 days of exposure and it was negative

    How acuate is the result ?

    Thanks a lot again

  18. dear Dr,

    1 month before a women masterbating me and it’s vagina fluid in his hand and contact my top side of penis and we involved deep French kissing and to I fingered it’s overy and finally she rub my penis top with his hand it full of vaginal fluid.
    After this I took HIV combo test and Elisa test exactly 32 days after this two come back negative and non reactive with index value of 0.240.
    My question is

    1.From above exposure any chance for infection
    2. HIV combo and ELSIA test after 32days from exposure later test on future it has any chance to turn positive.
    3. I read some website they are saying HIV test is conclusive after 3 month only.why?
    Please give your replay

  19. Hi doc,
    I tested p24 combo in 68days after protected vaginal and unprotected oral sex the result is negative the question is :

    I have G6pd do u think it will affect the HIV test result and i need to retest after 6months?

    Or 68 is fully conclusive?

    Please advice and help

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